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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5de0dca21a1e09a9baba3ed5f379b7d4ac2b08646523009d72687879c98843f2' 
  AND token = 'h3s6dtKiaIioKxOsemAGx00zFg38/rWAjXPNidOZl+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}