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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a40ca7537df005dca83e68fcfb0291b413a00e0d425dcabaca91fbb3ae59e8a7' 
  AND token = 'AiCPKInO/Ak0jO8DGE3yzqxTi6LgR/XQnEoLi+hCy40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}