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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a1940eed7936a1b0d531362d9c5008c367f9646011d60a8ea1192d60aa1adf23' 
  AND token = 'HshlRzGyNT/bw7tE28rhOKKfPLxfnd0A1k44pFbgUKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}