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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2167dcca702d2854a9878977b2e77f58bc8a7c6391bb573a496952e4772a80b1' 
  AND token = 'PtDHN4AiLi8esalwubgKgMcqg0gMM76+R2iA58WdUps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}