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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1f5899c54242d7453931a1ee9e840dfb09f60caf9700a9d1c3d4b3d7293d82c1' 
  AND token = 'NWyn60GDN3hlwckHskac0KoQqxJryGlfhmcHFh6dU84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}