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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43973b97cd6e429d0726dfc3a7180b5311c7c959ed9d2914b97b8b2187fc0c61' 
  AND token = 'o7MbUFSRIy1LKGUf53bSs0TudrZzEYrHQaX581VRg/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}