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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7ecf4ebd62499ba81337904d86344714ad28b889a9ed567ae76e0c5730bed2c' 
  AND token = 'Q4Kp/qT2702is3B3eAPaGR+8G3UOVw+Wqn/kpRJT9iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}