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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ce1a3b26c403a67fb3a960f3cbb66051c980563bed6158b30edf0a166c6894ec' 
  AND token = 'lJZE+sAg4h0/vy3sPLoK3y5P5tcsRFxIDAcIg3neNeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}