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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b4f5c579123e40aa58b0963ab911531506da4f89abf4e799ed96e4c424549b4' 
  AND token = 'JGuBAyKpmcsj6DXpwE0tapxU5/XcZOaulegqL8d1eXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}