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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '619ffc742c3a3d79a12f8fb84663f5dda40fa0097a575d7a564ed20f6945c30a' 
  AND token = 'naMrDyJIAjeLii0mVGXOuTEMOadj6KrZYEu/tz4Xs40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}