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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '377e85090fd2a52fa0a13df2da21cc264fa1106f27073b88c1b3cf470bc2bd15' 
  AND token = '1pqbwKHw3yWRnSbNlqNyDIUQRqfJ9560XcrreNajROI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}