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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '26737610ee95e9f0d0cc45e0404ab15c11be49bf4dd144f6459163c9c9546af2' 
  AND token = 'gziMGcTuB/iCBy9simRPK55CmNJnWgJbzz0XnZqAUOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}