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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5058ab94b4d2134aaad17a2d2582094c095ca775b14e1b23173038dbbd1224b2' 
  AND token = 'uIS+rCAw3+GMyD1D4PlT1m6IPSrjepMCEdHJXD13vZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}