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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8a723121e18d058fc93b3c7cc52e21f8a2d12fbd979b2fb2c14b5cff0d157dd3' 
  AND token = 'FOHExkDjR3885ELWhhS0FJrwk0uh7aPwf+ySs45WZTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}