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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d0bbda8a209fbab7af410e96fa9bd065bf66ecc2131212ad2c29fade778305f' 
  AND token = 'odz924+hS4uox6cvRhIld5BDuF4vGpqZsobNauDEx0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}