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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '47d5a6f774c2e343ed5fbff4bf1ddfd18d3b391a48f01f58ebc377b001f32524' 
  AND token = 'JYveAAJ0n/KqSIPIDnufZq8O0RRxUHSi1nJYw/4Pqyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}