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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ae6b784672e0f0b90175282f6bd7fb8f0557eb07691d114aca01010a0bd3228' 
  AND token = 'ENcSRJEJTTTqIXTaqpmiyFXakeI3MiQxUmsQM/mE1uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}