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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '08da021feda40be05d9a8900a818d7175ea530edee301a02384a2263690f2c03' 
  AND token = 'r0+RuSgDXgjUXXMQhJ5BX10EQtpTg3KzimuUbIwBPs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}