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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb2a7d31502d87a53939ad4a8ffde13ee3c79ef93637fe704b27c42acd852a4d' 
  AND token = '54nSK8QORYA2MIWhhUP0IUQnG2g+OmlXM0bzg+8Rp8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}