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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4d2858a51387c9e6c7b1cede29509ada2a99097a36b4e35b1447e377adaf1c00' 
  AND token = 'cTviZ7TpO94rrI2CJptOTwGhltfVtXxPAbHVNCwJI6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}