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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43aa2651412575e0555a7512fc618071e23a90d70309d45a39ab3f514f8bedbc' 
  AND token = 'VaWaXrDJyaOGvE+5Fmoa1qy4z7HujEbBLOkVfEbHAOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}