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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '95a417aef8c114b1c646cf974fe48cd659dd645aa0f51824dd38599546a38ead' 
  AND token = 'MwWdqkczR/vRWa6kT1iOuDS35i6+H4IZArVrZimBj00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}