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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66e012fa151f1a7d561ff517ebfcefec7dcf4551e3a7440e90175234b766c3bc' 
  AND token = 'XNrBNAaPjNcr+mey8pN2SXVP7CJ9rrBlrdFGhl41LnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}