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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a42f0cbaa1f89a2322afc11bd9cc2def029a1827a90c62132858c7226df6e412' 
  AND token = 'zNnuVRYJjqlrwBFyLcI1jRTcMtVWAdEqyBlABOLoUBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}