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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '549865a27dbc8dc4d14e3f158250d00e737d80e7c65400c7a0e66d9b8dabeae8' 
  AND token = 'KcoFF6q6EJLeFniTaBbA9jI9gBlf0PW3df38wtHUCBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}