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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42168d54cfa433a33d3a184329af8be21a96200d911172c819a7f0f1b0e40b4d' 
  AND token = 'ftgHEa/xClKsXdOezRBIAUJih10/hkg2qTwCa2bBZsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}