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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c821e46c5b35212b67c1584d75c41584a297381b3cca550a707b49c9eb3cd88a' 
  AND token = 'HUhO2W7LW8IBkS9G8m6Id8O7lWzs8GRNq/XPDKtUMIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}