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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fb74f952978643ffe8f6d3992d4db0301f730d2d994895efee53785bb1d1ddcf' 
  AND token = 'AAqEDyKY8GdTLBT5lpH4pU+3dCHoXsAzmSXeNjVpzkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}