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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8279822f36d456f2f7a4abe1d4652dc4e0f125b21a9014a50328e56fb86e27c8' 
  AND token = 'xLkVRglz4d5dF2y8l65APAjrAzX6TjmfKVf0GIUYvaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}