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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6e1c7d6a17451b7b60e76bbb75989ff3bf30911f3589f3a3abc9fcedd1d0f417' 
  AND token = '1neA6KbeigBGvPI5/EmYLRf5UWc6/tZeHfZhxmWd2NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}