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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6e8d61c3ea118228aa2a9fbf3df4f129ba63804c7e54e1996947336688dc2fd8' 
  AND token = 'xRZQeTMU0ePsOg5SCszWmdz+jaSj2ykQMD9uaB6PwEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}