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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c79d50d9dbb278de893e8f7e3a150ec312336416bcd335270d1a70f13fa3eda9' 
  AND token = 'uQ2X3Ozmdmk758sVqZ0d8FVdbOdjHbq8kuxql8FMg1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}