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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1915c5f9fcb21c88ab6fe9714a703adce15e57aa36246654c7619c746e443221' 
  AND token = 'b00SqPOjVRErYWrsnPefdsWOc0yB5jOiGnmiKfyThvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}