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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed8b89f978ac236519de5ebd85f1c9de72217b45fc5b5e4b8e480be94b380052' 
  AND token = 'lpLQ1pnRmUQO0fkV2HqHA4kNt+u0n0cHvGThBLwrbsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}