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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '18a0808ec5ac3658e5098d69a73dc786ae4cf3650b8ac413eb8ca35864629aea' 
  AND token = 'QOfC8zzrDSQOkqGbxqEz8rLG78jx3AzAjlkInpKOAHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}