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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0c4d1d9c0e2210313b5a5919fd47c66073ab0d81c5c89c9147df78d4449d101' 
  AND token = 'JwwwYdTD9cdPDmkZCrFtGd9YBTEEl4OrJDL4i0CGPeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}