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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50c20d70ff0971e0a39476465f56ccdcaba989d5bf808a33b2edd8b9e1141862' 
  AND token = 'gs+rwEaawGk+pTTbSPy4JL2C45EgWT0PetRoizZFl4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}