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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5595e05f06d8e7c1156eed970c8cae6f3153f02d6f66218147383a0839beaf82' 
  AND token = 'zPJmw01UOznfVSEaCrNpdFq+EPEsQoxgs9sgf5Jb0Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}