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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '44ca54178f2cf58759ef3c881f8c6d106f29a999b861744e04190b7eb72ce0aa' 
  AND token = 'MwyWtPgKZXssXUoe9XXPCYkH1LQtKnQvPNOemXQAZZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}