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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '75f59b398676f48e90460e5a480f60c5e28536a7309aef58d66d63f5d6ba20fe' 
  AND token = 'NtTrKsngVay79KBTA1Td4POw8mkSCDR5ylUhliERHuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}