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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7fc699255f1cdf8ec9cb87615e771e5cc91d2693e3ff7a199f8a468b18d1a8de' 
  AND token = 'b2G8t/TKYinuWC/NidbkFEjcbZawjvdhtuGuDDGw/Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}