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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9ee25f715912ed48f4ee84aa007e6f7947f253171717f9f8f3f91463da6e0f1a' 
  AND token = 'R45Bye8EJjauwehrvRqOs02FWuGWOgoCduLN80siTCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}