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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '278075f992d90a970e8bdb3e47af970d3148b46cbd04c3ec266d97b6bf0d760b' 
  AND token = 'HVL38AMk+tim29tU+l0PQ6mamAERQK8K9gTt+zrgLLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}