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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e6d080c3a424822d8556f0a2dd2fe7b8760e6dc40d73c0d57e3b608bd0c4f2a5' 
  AND token = 'PGlwqJnePfrkp7ETih2+ndk0DOw/OTgiwbvgqFIqEqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}