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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64378ee0a68104c6950059820af9fbe1d4594edb875f157127ecf12757f82f52' 
  AND token = 'p/oX65qxvhh5cT0bhclZZkOdQJTKdMDw2cRiLBxJMxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}