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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f084821e830f8b3b42abba3a91a6c5c63f4bbff81e0fa6a77dda41327a57f1c' 
  AND token = '9k2cw0SyuEvGkPwCnhW+zJq8cQVTt4hJ43zLq1LA4Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}