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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f3a09664845b6e584f9b28f8264ff619099804dca308e63972fd29674f8e2244' 
  AND token = 'xLO3OJv0RAsE420rH/9ZPzBjB+a+eRIMLXZqPrpzaiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}