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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b43d3293f9e858513083714d12b4bda5606ed3ddc997b022809c0ef48e667256' 
  AND token = 'FP7FtY9SIReVp3Lu6/pJ9tbr6Op722EkArC8mP6AAlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}