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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '649ab1720c572fa75f93a931b851e3dec2347496b91b49163c52499cc5bfcff6' 
  AND token = 'dEpRfAxnT4Th7DUAb0imdqKk+uCWnzo7nnfMoxSrt0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}