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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1be72c6ff27705d86e5d2f6982e15438fac018b444b19148e7e85281c0a9246e' 
  AND token = 'wXjIF2mnVEpI2yFxsIyvwebU4JcwblPZfC2su8WnIWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}